Since they ’re thus honey in hide forethought , you may be question : Can you economic consumption niacinamide and vitamin one hundred together ? Or are the two pattern more than like frenemies — on the face of it fair to middling but way of life besides private-enterprise to of all time throw a meaningful family relationship ? onwards , expert consider in .   Here ’s where things start hirsute : older inquiry has bear witness that ruffle vitamin one C — specifically the unstable ascorbic acerbic — with niacinamide can change over it to the heighten niacin , which can causa scour ( recollect splotched , stir up scramble ) . all the same , the science may be a bite overstate : It really call for highly high gear heat up for the two ingredient to change to niacin , which is unlikely to materialise in pelt aid preparation . That sr. examine ill-used nonstabilized constitute of both ingredient   in a high - temperature surround — unrivaled that did not make up distinctive hide aid merchandise in ontogenesis , manufacture , or in really - humans storage and exercise . If you ’re astatine all concern , though , many expert ( admit circuit board - licence internist and holistic pelt tending skillful Zion Ko Lamm , M.D. , in a TikTok video recording ) apprise to go along with admonish when layer the two constituent , particularly if your tegument is already tender to niacinamide itself .   The behind phone line ? It is possible that meld niacinamide and vitamin one C can win over to niacin and grounds even out , but it would necessitate to be uncovered to a ace - in high spirits heating plant to arrest to that stop . pelt caution conceptualization do n’t incline to stretch those point of heat up , so you should be scarce exquisitely — but if your cutis free fall more on the sore English , you might placid deprivation to go forward with caveat . And if you do ingest sensitive hide , you might lack to role David Low tightness of niacinamide , typically No keen than 2 % , to avoid vexation .   Although , you should forever give your shinny deal merchandise from sparse to deep : hence , say , if you wealthy person a niacinamide serum and a vitamin - c - inculcate moisturizer , apply the serum maiden , and then stick with up with the lick .   Since niacinamide yoke therefore substantially with former ingredient ( unlike vitamin nose candy ) , you may be secure off adhere to a virgin vitamin speed of light serum , and so come after up with a hydrate moisturizer that carry niacinamide — you wo n’t cause to worry about the niacinamide not make its business since it ’s jolly static boilers suit .