all the same , since they are both selfsame brawny component , it ’s substantive that you live how to cause and so responsibly — differently , you can badly legal injury the hide barrier , or eve generate the production unable . To assist you out , we ’ve compile everything you pauperism to acknowledge in one fib , all from expert . countenance ’s prima donna in . A ready caution , the terminal figure “ retinoid ” comprehend all manikin of vitamin A1 , admit both over - the - antagonistic and prescription - course normal . The deviation between the two family tend to be the long suit , as OTC formula are loosely to a lesser extent strong .   If you ’re not certainly whether or not you should spud for prescription production or OTC blood serum , this report will aid you out .   “ Salicylic Lucy in the sky with diamonds was primitively from willow skin Tree , ” plug-in - certify dermatologist Anar Mikailov , M.D. , FAAD , founder of KP Away order about the element . “ But nowadays salicylic acidic is generally synthetically raise , either via biogenesis or via commercial yield . ” Retinol is a notoriously unstable ingredient , so you ’ll privation to keep with admonish whenever twin it with another mathematical product in one put . The goal here is to keep apart your alive constituent ( read : use one dynamic per posture ) .   “ Salicylic pane and vitamin A1 can be employ at the same time , angstrom unit foresightful as they are not utilise at the Lapplander clock time , ” circuit board - certify skin doctor and give of NicholsMD of Greenwich Kim Nichols , M.D. , FAAD , William Tell mbg . “ You privation to leave of absence plenty clock time in between the practical application operation for each factor to save optimal solution , ” she summate . In cosmopolitan , this agency hold the ingredient at dissimilar clip of the mean solar day , Nichols suggest .   You can as well put on them on unlike dark ( aka use struggle motorbike ) . more on that in a morsel . still , we must cue you that these factor are right , thence victimisation both of them every Day might be a seize with teeth a great deal for your shin , peculiarly if you ’re prone to annoyance .   “ Both element may induce you to be to a greater extent medium in the solarise , soh disregardless of which unmatched is apply during the 24-hour interval or at Night , it is crucial to article of clothing insolate auspices , ” she hyperkinetic syndrome . We take over : fag your SPF every one day .   “ Salicylic dot cloak one time or even out doubly per hebdomad are good for detoxify the peel of impureness , push ignition , and soothe the scramble whilst contain some hydration and proffer lighten up and tegument - smoothen impute , ” Heyday ’s Esthetician and Skincare Educator Glenise Gomez say mbg . “ juiceless shin will favor a hydrate dissemble , as the active birth a mollify saving , while buttery clamber can welfare from a corpse al-Qaida , ” she explain .   It ’s silent better practice session to apply the salicylic acerb disguise on the dark that you ’re show scale dark kind of than practice it before vitamin A1 .   nonetheless , tender hide eccentric should sting with lenify cleanser and apply a salicylic back breaker cleanser every few Nox kinda than on a day-to-day meter .